CONTRACEPTIVE VAGINAL SUPPOSITORY CONTAINING nONOXYNOL-9 AND ZINC ACETATE SALT IN A CLINICAL TRIAL
نویسندگان
چکیده
منابع مشابه
Safety of a nonoxynol-9 vaginal gel in Kenyan prostitutes. A randomized clinical trial.
OBJECTIVE To evaluate the safety and toxicity of once-daily administration of Advantage-24 (Columbia Research Laboratories, Inc., Rockville Centre, NY), a vaginal gel containing 52.5 mg of nonoxynol-9 (N-9), including the effects of this gel on the vaginal and cervical epithelium. STUDY DESIGN Randomized, placebo-controlled, double-blind crossover trial, with a 2-week product application peri...
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Crude decoction of Chenopodium album seed showed spermicidal effect at MIC 2 mg/ml in earlier studies. Systematic isolation, characterization and evaluation revealed that the major metabolite Desgalactotigonin (DGT) is the most effective principle in both in vitro and in vivo studies. The in vitro studies comprises (a) rat and human sperm motility and immobilizing activity by Sander-Cramer assa...
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Background. Renal colic is a medical emergency due to the rapid onset and devastating nature of its pain. Opioids and nonsteroidal anti-inflammatory drugs (NSAIDs) are both used as first-line choices in its management. Aim. This study aimed to compare the efficacy and safety of opioids and NSAIDs in the management of acute renal colic. Methods. One hundred and fifty-eight patients were divided ...
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OBJECTIVE To gain a greater understanding of published safety data for candidate vaginal microbicides. DESIGN A systematic review of human safety trials of candidate vaginal microbicides - agents designed to protect women against HIV and other sexually transmitted infections. METHODS Trials were published in peer-reviewed journals, and publication cut-off was August week 4, 2008. Trials of ...
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BACKGROUND AND OBJECTIVES There are conflicting opinions on whether to recommend spermicides containing nonoxynol-9 for prevention of sexually transmitted diseases, including human immunodeficiency virus (HIV). GOAL To systematically review and summarize the medical literature on the effect of spermicides containing nonoxynol-9 on prevention of gonorrhea, chlamydial infection, and HIV. STUD...
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ژورنال
عنوان ژورنال: Journal of Drug Delivery and Therapeutics
سال: 2013
ISSN: 2250-1177
DOI: 10.22270/jddt.v3i1.354